Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193468 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1USP2KDM4E | |
| SCHEMBL5193499 | 0.81 | FAAH (0.52) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL5195658 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL5193934 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1USP2KDM4E | |
| SCHEMBL5193950 | 0.77 | CCR2 (0.46) | KMT2AMEN1L3MBTL1USP2NPSR1 | |
| SCHEMBL5213606 | 0.76 | KMT2A (0.60) | ALDH1A1KMT2AMEN1GAAKDM4E | |
| SCHEMBL5194022 | 0.74 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL5190181 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL5206456 | 0.74 | MAPK1 (0.58) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL5193560 | 0.74 | CCR2 (0.48) | ALDH1A1KMT2AMEN1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |