Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193739 | 0.87 | PKM (0.56) | KMT2AMAPTALDH1A1MEN1RAB9A | |
| SCHEMBL5193432 | 0.83 | MAPT (0.50) | KMT2AMAPTMEN1RAB9APKM | |
| SCHEMBL5193979 | 0.81 | NAMPT (0.54) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL5193199 | 0.80 | MAPT (0.55) | KMT2AMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5194091 | 0.79 | FAAH (0.53) | KMT2ANPC1ALDH1A1MEN1RAB9A | |
| SCHEMBL16178503 | 0.78 | MAPT (0.59) | KMT2AMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5190775 | 0.78 | MAPT (0.49) | KMT2AMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5210355 | 0.76 | CCR2 (0.50) | KMT2AMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL6716470 | 0.74 | MAPT (0.65) | KMT2AMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL5190612 | 0.73 | KMT2A (0.58) | KMT2ANPC1ALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |