Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 13/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190160 | 0.82 | — | — | |
| SCHEMBL5195330 | 0.77 | CHRNB2 (0.37) | EPHX1ALDH1A1GAAMAPK1HTT | |
| SCHEMBL5195467 | 0.73 | NPSR1 (0.35) | — | |
| SCHEMBL2911232 | 0.72 | SLC6A1 (0.32) | ALDH1A1 | |
| SCHEMBL28436498 | 0.71 | EPHX1 (0.53) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL8803180 | 0.70 | CCR2 (0.39) | NAAAEPHX1 | |
| SCHEMBL30404697 | 0.70 | ALDH1A1 (0.40) | NAAAALDH1A1NPC1RAB9A | |
| SCHEMBL172322 | 0.69 | MGAM (0.38) | ALDH1A1GAA | |
| SCHEMBL123309 | 0.69 | MGAM (0.38) | ALDH1A1GAA | |
| SCHEMBL27853467 | 0.69 | GRIK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |