Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196161 | 0.89 | RAB9A (0.46) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5195687 | 0.84 | CYP1A2 (0.47) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL5197734 | 0.84 | POLB (0.49) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5196876 | 0.83 | SMN1; SMN2 (0.53) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3811484 | 0.75 | ACLY (0.43) | MAPTGRM1LMNAL3MBTL1TP53 | |
| SCHEMBL5196996 | 0.75 | ADORA3 (0.51) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5194116 | 0.75 | USP2 (0.40) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5195341 | 0.73 | CYP1A2 (0.44) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5193749 | 0.73 | CYP3A4 (0.50) | ALDH1A1NPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL5196153 | 0.72 | SMN1; SMN2 (0.55) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |