SCHEMBL5197167

SCHEMBL5197167

C[C@H]1O[C@H]1COC(=O)CCC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
TLR4 O00206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259020 0.81 DGKA (0.41) MAPTLMNAPOLB
SCHEMBL10071438 0.79 NLRP3 (0.43) MAPTTLR4
SCHEMBL258844 0.79 DGKA (0.44) MAPTLMNAPOLB
SCHEMBL1252907 0.79 PRKD3 (0.33) MAPTTLR4
SCHEMBL10071466 0.76 DGKA (0.46) MAPT
SCHEMBL10071472 0.76 MAPT (0.33) MAPTLMNAPOLB
SCHEMBL28397505 0.75 ALDH1A1 (0.47) LMNAPOLB
SCHEMBL8432072 0.75 TSHR (0.42) LMNAPOLB
SCHEMBL10071467 0.75 DGKA (0.53) MAPTLMNA
SCHEMBL10071446 0.75 NAAA (0.38) MAPTTLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403260-B1 Optically active epoxy compounds and processes for their production TOSOH CORP (JP) 2007-08-08 EP disclosed
US-7169944-B2 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2007-01-30 US disclosed
US-20040063979-A1 Optically active epoxy compounds and processes for their production TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403260-A2 Optically active epoxy compounds and processes for their production Tosoh Corporation (JP) 2004-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063979-A1 Optically active epoxy compounds and processes for their production CYP51A1, CYP11B1, PTGES MAPT 4136/4885LMNA 1688/4885POLB 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.