Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890577 | 0.82 | CHRM1 (0.51) | — | |
| SCHEMBL10778320 | 0.81 | ADH1A (0.45) | L3MBTL1ADH1CADH1AMEN1ALDH1A1 | |
| SCHEMBL5195333 | 0.78 | MAPT (0.39) | L3MBTL1ADH1CADH1AMEN1ALDH1A1 | |
| SCHEMBL5197653 | 0.78 | MAPT (0.39) | L3MBTL1ADH1CADH1AMEN1ALDH1A1 | |
| SCHEMBL4707858 | 0.76 | AVPR1A (0.39) | USP2 | |
| SCHEMBL3891941 | 0.75 | OPRM1 (0.43) | L3MBTL1ADH1CADH1AOPRM1OPRD1 | |
| SCHEMBL5459487 | 0.72 | SLC6A4 (0.40) | L3MBTL1ADH1CADH1AOPRM1OPRD1 | |
| SCHEMBL5449617 | 0.72 | SLC6A4 (0.40) | L3MBTL1ADH1CADH1AOPRM1OPRD1 | |
| SCHEMBL11529348 | 0.66 | ADH1A (0.41) | L3MBTL1ADH1CADH1AMEN1ALDH1A1 | |
| SCHEMBL31231682 | 0.66 | ALDH1A1 (0.36) | MEN1ALDH1A1LMNAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773829-A1 | AMINO-TROPANE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006021657-A1 | AMINO-TROPANE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |