SCHEMBL7597284

SCHEMBL7597284

Cc1nc2ncnn2c(O)c1Br.[NaH]

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 2/20 0.42
TSHR P16473 2/20 0.40
ENPP1 P22413 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
USP2 O75604 1/20 0.38
MBOAT4 Q96T53 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 3/20 0.36
MAPK1 P28482 2/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457105 0.98 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL7553783 0.88 LMNA (0.43) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL5199168 0.80 TSHR (0.50) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL9824226 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL6264484 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRENPP1USP2
SCHEMBL7117782 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL24129443 0.76 ENPP1 (0.56) ALDH1A1ENPP1
SCHEMBL9770335 0.76 HSD17B10 (0.56) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL5197330 0.75 MEN1 (0.55) ALDH1A1HSD17B10TSHRENPP1L3MBTL1
SCHEMBL5672150 0.73 TSHR (0.41) ALDH1A1HSD17B10TSHRENPP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0772079-B1 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK CO (US) 2002-12-11 EP disclosed
US-5792601-A MODIFYING THE PERFORMANCE PROPERTIES OF THE HIGH CHLORIDE SILVER HALIDE EMULSION BY A COMBINATION OF SILVER BROMIDE ADDITION, IRIDIUM DOPANT INCORPORATION AND ANTIFOGGANT ADDITION EASTMAN KODAK COMPANY (US) 1998-08-11 US disclosed
US-5736310-A SILVER IODOCHLORIDE GRAINS GROWN IN DISPERSING MEDIUM; EMPLOYING GRAINS AS SUBSTRATES FOR FURTHER GRAIN GROWTH EASTMAN KODAK COMPANY (US) 1998-04-07 US disclosed
US-5728516-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-17 US disclosed
US-5726005-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-10 US disclosed
EP-0772079-A2 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK COMPANY (US) 1997-05-07 EP disclosed
EP-0718676-A1 Photographic print elements containing emulsions of enhanced speed and controlled minimum densities EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed