Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765844 | 0.84 | POLB (0.56) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL5199244 | 0.83 | LMNA (0.49) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2702562 | 0.83 | RAB9A (0.63) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20528915 | 0.82 | GPR35 (0.38) | LMNAKMT2AMEN1JAK3POLB | |
| SCHEMBL4085439 | 0.81 | NPC1 (0.57) | MAPTALDH1A1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL8880595 | 0.78 | KDM4E (0.60) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11403762 | 0.77 | NLRP3 (0.62) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL3715355 | 0.77 | GAA (0.72) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1040883 | 0.77 | ALDH1A1 (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7133734 | 0.77 | MAPT (0.50) | LMNAKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469845-B1 | DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | KALIL FIHLO JORGE ELIAS (BR) | 2007-08-15 | — | — | EP | disclosed |
| EP-1469845-A2 | COMPOUNDS, PARTICULARLY OF UREA DERIVATIVES OR ESTER DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | Kalil-Fihlo, Jorge Elias (BR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063858-A2 | COMPOUNDS, PARTICULARLY OF UREA DERIVATIVES OR ESTER DERIVATIVES OF HALOACETAMIDOBENZOIC ACID AND USE THEREOF FOR THE TREATMENT OF PARASITIC DISEASES | KALIL-FIHLO, JORGE, ELIAS (BR) | 2003-08-07 | — | — | WO | disclosed |