Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376702 | 0.68 | GAA (0.73) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL5604987 | 0.68 | GAA (0.73) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL10054998 | 0.68 | GAA (0.73) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL1884341 | 0.68 | GAA (0.73) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL27547071 | 0.66 | GAA (0.70) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL18416413 | 0.64 | TDP1 (0.50) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL990038 | 0.64 | TDP1 (0.70) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL841689 | 0.64 | TDP1 (0.70) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL66892 | 0.64 | TDP1 (1.00) | TDP1GAAALDH1A1TSHRLMNA | |
| SCHEMBL6242838 | 0.63 | TDP1 (0.61) | TDP1GAAALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284981-B1 | METHOD FOR PRODUCING TRANSITION METAL COMPOUNDS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2007-07-11 | — | — | EP | disclosed |
| US-7105690-B2 | Method for producing transition metal compounds and their use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20030191334-A1 | Method for producing transition metal compounds and their use for the polymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191334-A1 | Method for producing transition metal compounds and their use for the polymerization of olefins | PPOX, PORCN, FASN | TDP1 4123/4885GAA 3341/4885ALDH1A1 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.