Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657767 | 0.78 | — | — | |
| SCHEMBL2658515 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL2657607 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL2658679 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL14336758 | 0.74 | PLAU (0.41) | PLAU | |
| SCHEMBL2658418 | 0.69 | TDP1 (0.34) | — | |
| SCHEMBL648206 | 0.68 | TDP1 (0.40) | — | |
| SCHEMBL22893013 | 0.68 | PLAU (0.35) | PLAU | |
| SCHEMBL676974 | 0.67 | TDP1 (0.39) | — | |
| SCHEMBL10793637 | 0.67 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-06-24 | — | — | US | disclosed |
| US-7312236-B2 | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312236-B2 | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1697305-B1 | SUBSTITUTED (4-AMINOCYCLOHEXEN-1-YL)PHENYL AND (4-AMINOCYCLOHEXEN-1-YL)PYRIDINYL COMPOUNDS AS 5-HT1F AGONISTS | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20070078169-A1 | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists | ELI LILLY AND COPANY | 2007-04-05 | — | — | US | disclosed |
| US-20070078169-A1 | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists | ELI LILLY AND COPANY | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078169-A1 | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists | HTR1F, HTR1A, HTR1E | PLAU 1888/4885 |
| US-11858910-B2 | Pyridinylmethylenepiperidine derivatives and uses thereof | HTR1F, HTR1A, HTR5A | PLAU 1510/4885 |
| US-20210188803-A1 | PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF | HTR1F, HTR1A, HTR5A | PLAU 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.