Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | FURIN | P09958 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542687 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL6999270 | 0.85 | PBRM1 (0.58) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL8543766 | 0.83 | ALDH1A1 (0.55) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL520073 | 0.82 | HDAC8 (0.63) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL29944867 | 0.82 | HDAC8 (0.63) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL9921285 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL8302175 | 0.81 | F2 (0.56) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL2127722 | 0.81 | PTGS1 (0.77) | SMN1; SMN2NPSR1HSD17B10PTGS1ALDH1A1 | |
| SCHEMBL294944 | 0.80 | KDM4E (0.66) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 | |
| SCHEMBL6159659 | 0.80 | KDM4E (0.62) | SMN1; SMN2NPSR1HSD17B10PTGS1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590123-B2 | For cancer theapy | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | 2003-07-08 | — | — | US | disclosed |
| US-20020022747-A1 | Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same | BEKESI GEORGE J (US) | 2002-02-21 | — | — | US | disclosed |
| US-6294695-B1 | HALOACETOAMIDOBENZOYLUREAS OR ETHYL HALOACETOAMIDOBENZOATES | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022747-A1 | Aminobenzoic acid derivatives having anti-tumorigenic activity, methods of making and using the same | ABAT, DDC, GABBR2 | SMN1; SMN2 4137/4885NPSR1 4692/4885HSD17B10 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.