Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790338 | 0.73 | TSHR (0.31) | — | |
| Bromide SCHEMBL8691064 | 0.72 | — | — | |
| SCHEMBL9212091 | 0.69 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15676570 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL2000947 | 0.67 | — | — | |
| SCHEMBL10852907 | 0.66 | — | — | |
| SCHEMBL10824119 | 0.63 | MEN1 (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9535269 | 0.63 | MEN1 (0.35) | — | |
| SCHEMBL11522975 | 0.62 | LMNA (0.31) | — | |
| SCHEMBL4088418 | 0.62 | CTH (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817034-A1 | M1 AND/OR M3 RECEPTOR ANTAGONISTS IN COMBINATION WITH OTHER ACTIVES FOR TREATING RESPIRATORY DISORDERS | SCHERING CORPORATION (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006047427-A1 | M1 AND/OR M3 RECEPTOR ANTAGONISTS IN COMBINATION WITH OTHER ACTIVES FOR TREATING RESPIRATORY DISORDERS | SCHERING CORPORATION (US) | 2006-05-04 | — | — | WO | disclosed |