Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.91 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrapropylammonium SCHEMBL59838 | 0.95 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL5490456 | 0.95 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL5430846 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL9262304 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL3892260 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL2723643 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL2723645 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL6658470 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL4552588 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL9302417 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013808-B1 | ISOTHIAZOLINE COMPOUNDS SUBSTITUTED WITH A CARBOBICYCLIC GROUP | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3013807-B1 | NAPHTHYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2020-04-08 | — | — | EP | disclosed |
| CN-105473584-B | Thiophene-or furan-substituted isothiazoline compounds | 勃林格殷格翰动物保健美国公司 | 2020-01-31 | — | — | CN | disclosed |
| US-10327446-B2 | Naphthyl- or isoquinolinyl-substituted isothiazoline compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-06-25 | — | — | US | disclosed |
| EP-2794601-B1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| EP-3013822-B1 | THIOPHENE- OR FURAN-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS AS PESTICIDES | MERIAL INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9732051-B2 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20160374342-A1 | Naphthyl- or isoquinolinyl-substituted isothiazoline compounds | MERIAL, INC. (US) | 2016-12-29 | — | — | US | disclosed |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | MERIAL, INC. (US) | 2016-10-13 | — | — | US | disclosed |
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BASF SE (DE) | 2016-05-26 | — | — | US | disclosed |
| WO-2014206910-A1 | BICYCLYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014206911-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014206908-A1 | ISOTHIAZOLINE COMPOUNDS SUBSTITUTED WITH A CARBOBICYCLIC GROUP | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014206907-A1 | NAPHTHYL- OR ISOQUINOLINYL-SUBSTITUTED ISOTHIAZOLINE COMPOUNDS | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2014-12-11 | — | — | US | disclosed |
| EP-2794601-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092943-A1 | ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-1434758-B1 | AMINONITRILE PRODUCTION | INVISTA TECH SARL (US) | 2007-08-22 | — | — | EP | disclosed |
| EP-1816120-A1 | Aminonitrile production | INVISTA Technologies S.à.r.l. (US) | 2007-08-08 | — | — | EP | disclosed |
| US-6455723-B1 | Aminonitrile production | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145223-A1 | Bicyclyl-Substituted Isothiazoline Compounds | BROX, TUBA3C, SYMPK | SLC22A1 2757/4885SLC22A2 2984/4885ALDH1A1 2335/4885 |
| US-20160297808-A1 | Thiophene- or furan-substituted isothiazoline Compounds as Pesticides | PTMS, DDT, PIR | SLC22A1 2913/4885SLC22A2 3241/4885ALDH1A1 1576/4885 |
| US-20160374342-A1 | Naphthyl- or isoquinolinyl-substituted isothiazoline compounds | IPO5, SNX1, IPO9 | SLC22A1 4018/4885SLC22A2 4005/4885ALDH1A1 3018/4885 |
| US-10327446-B2 | Naphthyl- or isoquinolinyl-substituted isothiazoline compounds | IPO5, SNX1, IPO9 | SLC22A1 4018/4885SLC22A2 4005/4885ALDH1A1 3018/4885 |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | PIR, ACHE, INMT | SLC22A1 3270/4885SLC22A2 3493/4885ALDH1A1 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.