Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.91 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrapropylammonium SCHEMBL59838 | 0.95 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL5490456 | 0.95 | SLC22A1 (1.00) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL22801372 | 0.92 | SLC22A1 (0.77) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL584932 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL4552588 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL9302417 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL6658470 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL2723645 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL5200853 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrapropylammonium SCHEMBL5430846 | 0.91 | SLC22A1 (0.91) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852450-B1 | New trimer catalyst additives for improving foam processability | AIR PROD & CHEM (US) | 2016-12-14 | — | — | EP | claimed |
| US-9196907-B2 | Air electrode for metal-air battery, membrane/air electrode assembly for a metal-air battery having such air electrode, and metal-air battery | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2015-11-24 | — | — | US | disclosed |
| US-20130273442-A1 | AIR ELECTRODE FOR METAL-AIR BATTERY, MEMBRANE/AIR ELECTRODE ASSEMBLY FOR A METAL-AIR BATTERY HAVING SUCH AIR ELECTRODE, AND METAL-AIR BATTERY | KYOTO UNIVERSITY (JP) | 2013-10-17 | — | — | US | disclosed |
| CN-103201884-A | Air electrode for metal-air battery, membrane/air electrode assembly for metal-air battery having the same, and metal-air battery | TOYOTA MOTOR CO LTD | 2013-07-10 | — | — | CN | disclosed |
| WO-2012056301-A1 | AIR ELECTRODE FOR METAL-AIR BATTERY, MEMBRANE/AIR ELECTRODE ASSEMBLY FOR A METAL-AIR BATTERY HAVING SUCH AIR ELECTRODE, AND METAL-AIR BATTERY | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2012-05-03 | — | — | WO | disclosed |