Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207414 | 0.91 | L3MBTL1 (0.55) | L3MBTL1CTSKPKMMAPK1TSHR | |
| SCHEMBL5924778 | 0.81 | CTSK (0.44) | CTSKCYP3A4FDPSITGB3ITGA2B | |
| SCHEMBL2398131 | 0.81 | CTSK (0.44) | CTSKCYP3A4FDPSITGB3ITGA2B | |
| SCHEMBL4385669 | 0.74 | POLB (0.62) | L3MBTL1CTSKTSHRRAB9AALDH1A1 | |
| SCHEMBL3652453 | 0.74 | POLB (0.62) | L3MBTL1CTSKTSHRRAB9AALDH1A1 | |
| SCHEMBL5201378 | 0.73 | L3MBTL1 (0.54) | L3MBTL1CTSKPKMMAPK1TSHR | |
| SCHEMBL1696818 | 0.73 | CA1 (0.46) | L3MBTL1MAPK1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL20683487 | 0.73 | CA1 (0.46) | L3MBTL1MAPK1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8008631 | 0.73 | NPSR1 (0.53) | MAPK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6826832 | 0.73 | NPSR1 (0.53) | MAPK1TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817275-A1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060494-A1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-08 | — | — | WO | disclosed |