Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180530 | 0.89 | TDP1 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6180524 | 0.89 | TDP1 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5206343 | 0.84 | L3MBTL1 (0.43) | TBXA2RMRGPRX4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5202463 | 0.82 | TDP1 (0.42) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5202456 | 0.82 | TDP1 (0.42) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6177157 | 0.80 | TDP1 (0.43) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5201500 | 0.76 | LMNA (0.44) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5205573 | 0.76 | LMNA (0.44) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6175334 | 0.76 | PTGER4 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6175825 | 0.76 | PTGER4 (0.47) | TDP1LMNATBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |