Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180524 | 1.00 | TDP1 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5201504 | 0.89 | TDP1 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6177342 | 0.83 | L3MBTL1 (0.45) | LMNATBXA2RMRGPRX4CYP1A2CYP2C9 | |
| SCHEMBL5202456 | 0.82 | TDP1 (0.42) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5202463 | 0.82 | TDP1 (0.42) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6177157 | 0.82 | TDP1 (0.43) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5201500 | 0.78 | LMNA (0.44) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL5205573 | 0.78 | LMNA (0.44) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6175334 | 0.77 | PTGER4 (0.47) | TDP1LMNATBXA2RMEN1KMT2A | |
| SCHEMBL6175825 | 0.77 | PTGER4 (0.47) | TDP1LMNATBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |