SCHEMBL520157

SCHEMBL520157

CN1C(=O)Cc2cc(N)ccc21

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.49
ATAD2 Q6PL18 1/20 0.49
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
SMYD3 Q9H7B4 1/20 0.47
BMPR1B O00238 7/20 0.46
BMPR1A P36894 7/20 0.46
ACVRL1 P37023 7/20 0.46
ACVR1 Q04771 7/20 0.46
PKM P14618 4/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
IDO1 P14902 1/20 0.44
TGFBR1 P36897 3/20 0.43
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5506946 0.98 TRIM24 (0.48) TRIM24ATAD2ALDH1A1GAASMYD3
SCHEMBL12991998 0.85 ATAD2 (0.41) TRIM24ATAD2ALDH1A1GAASMYD3
SCHEMBL736131 0.84 ATAD2 (0.64) TRIM24ATAD2
SCHEMBL520474 0.81 ATAD2 (0.53) ATAD2BMPR1BBMPR1AACVRL1ACVR1
SCHEMBL30222138 0.79 TRIM24 (0.54) TRIM24ALDH1A1GAASMYD3BMPR1B
SCHEMBL434054 0.79 TRIM24 (0.54) TRIM24ALDH1A1GAASMYD3BMPR1B
SCHEMBL12706597 0.79 RAB9A (0.44) ATAD2ALDH1A1GAAMEN1KMT2A
SCHEMBL5116351 0.78 ATAD2 (0.57) ATAD2ALDH1A1GAABMPR1BBMPR1A
SCHEMBL1925311 0.78 PKM (0.59) TRIM24ALDH1A1GAASMYD3BMPR1B
SCHEMBL2643055 0.78 TRIM24 (0.49) TRIM24ALDH1A1GAASMYD3BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736854-A2 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4719391-A2 TRIPLE KINASE INHIBITORS Unogen Biotech Ltd. (US) 2026-04-08 EP disclosed
US-20260085050-A1 TRIPLE KINASE INHIBITORS UNOGEN BIOTECH LTD (US) 2026-03-26 US disclosed
EP-4514473-B1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL MYERS SQUIBB CO (US) 2026-02-18 EP disclosed
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2025-10-16 US disclosed
US-12435181-B2 Formulations capable of reacting with or removal of molecular oxygen LI SHENSHEN (US) 2025-10-07 US disclosed
US-12404239-B2 Modulators of BCL6 as ligand directed degraders CELGENE CORPORATION (US) 2025-09-02 US disclosed
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
WO-2025096771-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
WO-2025059429-A1 MODULATORS OF BCL6 FOR USE IN A METHOD OF TREATING A CANCER OR AN AUTOIMMUNE DISEASE BRISTOL-MYERS SQUIBB COMPANY (US) 2025-03-20 WO disclosed
EP-2134689-A2 INHIBITORS OF FOCAL ADHESION KINASE The Scripps Research Institute (US) 2009-12-23 EP disclosed
WO-2009016119-A1 SUBSTITUTED ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF TYPE I AND II DIABETES MELLITUS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-05 WO disclosed
WO-2009016119-A1 SUBSTITUTED ARYLSULFONYLAMINOMETHYLPHOSPHONIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF TYPE I AND II DIABETES MELLITUS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-05 WO disclosed
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US disclosed
WO-2008115369-A2 INHIBITORS OF FOCAL ADHESION KINASE THE SCRIPPS RESEARCH INSTITUTE (US) 2008-09-25 WO disclosed
WO-2007095188-A2 DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-08-23 WO disclosed
EP-1781642-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-05-09 EP disclosed
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent JOSYULA VARA PRASAD V N 2006-10-12 US disclosed
WO-2006016221-A1 OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-02-16 WO disclosed
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents LUEHR GARY W 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085050-A1 TRIPLE KINASE INHIBITORS ALK, ERBB2, ERBB3 TRIM24 3575/4885ATAD2 4111/4885ALDH1A1 2170/4885
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent OXA1L, MRPL21, RPS27L TRIM24 2295/4885ATAD2 1754/4885ALDH1A1 946/4885
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents OXA1L, OXSR1, OXER1 TRIM24 3823/4885ATAD2 1891/4885ALDH1A1 900/4885
US-12404239-B2 Modulators of BCL6 as ligand directed degraders BCL6, BCL6B, BCL3 TRIM24 371/4885ATAD2 1684/4885ALDH1A1 3481/4885
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders BCL6, BCL6B, BCL3 TRIM24 371/4885ATAD2 1684/4885ALDH1A1 3481/4885
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents OXA1L, OXSR1, OXER1 TRIM24 3093/4885ATAD2 1520/4885ALDH1A1 894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.