Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 7/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 7/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 7/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520157 | 0.98 | TRIM24 (0.49) | TRIM24ATAD2ALDH1A1GAASMYD3 | |
| SCHEMBL12991998 | 0.84 | ATAD2 (0.41) | TRIM24ATAD2ALDH1A1GAASMYD3 | |
| SCHEMBL736131 | 0.82 | ATAD2 (0.64) | TRIM24ATAD2 | |
| SCHEMBL520474 | 0.79 | ATAD2 (0.53) | ATAD2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL5505351 | 0.79 | ATAD2 (0.56) | ATAD2ALDH1A1GAABMPR1BBMPR1A | |
| SCHEMBL5503465 | 0.78 | ATAD2 (0.44) | TRIM24ATAD2ALDH1A1GAAMEN1 | |
| SCHEMBL5510757 | 0.78 | BMPR1B (0.48) | ATAD2GAABMPR1BBMPR1AACVRL1 | |
| SCHEMBL434054 | 0.78 | TRIM24 (0.54) | TRIM24ALDH1A1GAASMYD3BMPR1B | |
| SCHEMBL30222138 | 0.78 | TRIM24 (0.54) | TRIM24ALDH1A1GAASMYD3BMPR1B | |
| SCHEMBL12706597 | 0.77 | RAB9A (0.44) | ATAD2ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |