SCHEMBL6318148

SCHEMBL6318148

CCCCOC(=O)NC(C)(C)CO

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.47
ACHE P22303 14/20 0.46
ALDH1A1 P00352 1/20 0.45
ATM Q13315 1/20 0.42
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31759054 0.85 EPHX1 (0.47) EPHX1ACHEALDH1A1ATMHPGD
SCHEMBL8800335 0.84 ACHE (0.53) EPHX1ACHEALDH1A1ATM
SCHEMBL9264188 0.84 EPHX1 (0.46) EPHX1ACHEALDH1A1ATM
SCHEMBL11100479 0.82 EPHX1 (0.52) EPHX1ACHEALDH1A1ATMHPGD
SCHEMBL7397655 0.82 ACHE (0.47) EPHX1ACHEALDH1A1ATM
Ammonia Solution, Strong SCHEMBL27626603 0.81 EPHX1 (0.50) EPHX1ACHEALDH1A1ATMHPGD
SCHEMBL5201837 0.81 EPHX1 (0.43) EPHX1ACHEALDH1A1ATM
SCHEMBL7396836 0.81 EPHX1 (0.43) EPHX1ACHEALDH1A1ATM
SCHEMBL7773645 0.80 ALDH1A1 (0.48) EPHX1ACHEALDH1A1ATMHPGD
SCHEMBL30738163 0.80 NPC1 (0.42) EPHX1ACHEALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852731-B2 Antiviral compounds PFIZER (US) 2005-02-08 US claimed
US-20040242884-A1 ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY 2004-12-02 US claimed
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2025-02-13 US disclosed
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-6852731-B2 Antiviral compounds PFIZER (US) 2005-02-08 US disclosed
US-20040242884-A1 ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY 2004-12-02 US disclosed
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed
EP-1147093-A1 SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS Pfizer Products Inc. (US) 2001-10-24 EP disclosed
WO-2000044728-A1 SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER PRODUCTS INC. (US) 2000-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CBR3, C5, CBR1 EPHX1 2468/4885ACHE 2945/4885ALDH1A1 3438/4885
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 EPHX1 3612/4885ACHE 4263/4885ALDH1A1 2804/4885
US-20040242884-A1 ANTIVIRAL COMPOUNDS ZC3HAV1, IRF3, IFNAR1 EPHX1 3554/4885ACHE 3976/4885ALDH1A1 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.