Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 14/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829390 | 1.00 | EPHX1 (0.50) | EPHX1ACHENAAAHCAR2NPC1 | |
| SCHEMBL5201837 | 0.95 | EPHX1 (0.43) | EPHX1ACHEHCAR2RAB9A | |
| SCHEMBL3400195 | 0.82 | EPHX1 (0.43) | EPHX1ACHEHCAR2 | |
| SCHEMBL9030664 | 0.81 | EPHX1 (0.42) | EPHX1ACHEHCAR2NPC1RAB9A | |
| SCHEMBL21059108 | 0.79 | EPHX1 (0.60) | EPHX1ACHENAAA | |
| SCHEMBL19548070 | 0.78 | FPR2 (0.41) | EPHX1ACHEHCAR2NPC1RAB9A | |
| SCHEMBL11523990 | 0.78 | EPHX1 (0.59) | EPHX1ACHENAAAHCAR2NPC1 | |
| SCHEMBL21059244 | 0.78 | EPHX1 (0.63) | EPHX1ACHENAAA | |
| SCHEMBL27577278 | 0.78 | EPHX1 (0.63) | EPHX1ACHENAAA | |
| SCHEMBL7368744 | 0.77 | EPHX1 (0.44) | EPHX1ACHEHCAR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |