Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 20/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.49 |
| ▸ | GABRP | O00591 | 16/20 | 0.49 |
| ▸ | GABRD | O14764 | 16/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 16/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 16/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 16/20 | 0.49 |
| ▸ | GABRE | P78334 | 16/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 16/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 16/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 16/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 16/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055883 | 0.89 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4669520 | 0.87 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2835106 | 0.87 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL2469515 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL29397350 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL15088 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL44222 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6055919 | 0.87 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL7171206 | 0.87 | GABRP (0.59) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL3351877 | 0.86 | GABRP (0.58) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968578-A2 | POLYMORPHS AND AMORPHOUS FORMS OF 5-AMINO-l-[2,6- DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]-4- [(TRIFLUOROMETHYL)SULFINYL]-IH-PYRAZOLE-3-CARBONITRILE | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007069254-A2 | POLYMORPHS AND AMORPHOUS FORMS OF 5-AMINO-l-[2,6- DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]-4- [(TRIFLUOROMETHYL)SULFINYL]-IH-PYRAZOLE-3-CARBONITRILE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2007-06-21 | — | — | WO | disclosed |