⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188879 | 0.79 | — | — | |
| SCHEMBL8943155 | 0.78 | TDP1 (0.47) | — | |
| SCHEMBL80458 | 0.75 | — | — | |
| SCHEMBL29674842 | 0.75 | — | — | |
| SCHEMBL29481423 | 0.75 | — | — | |
| SCHEMBL571047 | 0.75 | — | — | |
| Fluoride SCHEMBL25169957 | 0.72 | CES2 (0.39) | — | |
| SCHEMBL8181149 | 0.72 | TDP1 (0.55) | — | |
| SCHEMBL112382 | 0.72 | — | — | |
| SCHEMBL3880085 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036680-A | Anti-fibrotic pyridones | 英特穆恩公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2024125437-A1 | GSPT1 DEGRADATION AGENT AND USE THEREOF | 南京圣和药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-112779023-B | Liquid crystal compound for high-frequency device | DIC株式会社 | 2024-03-01 | — | — | CN | disclosed |
| EP-4236659-A1 | LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE LIGHTEMITTING DEVICE, AND MIXTURE | Samsung Electronics Co., Ltd. (KR) | 2023-08-30 | — | — | EP | disclosed |
| CN-110452216-B | Anti-fibrotic pyridinones | 英特穆恩公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-3052501-B1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2022-06-22 | — | — | EP | disclosed |
| US-20220017484-A1 | INHIBITOR OF BRUTON TYROSINE KINASE | BEIJING RECIPROCAPHARMACEUTICALS CO., LTD. (CN) | 2022-01-20 | — | — | US | disclosed |
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| EP-2315751-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | Amgen Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| US-20110086834-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086834-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086834-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2010090737-A1 | PYRIDAZINONE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010090737-A1 | PYRIDAZINONE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-12 | — | — | WO | disclosed |
| US-20100197651-A1 | Pyridazinone compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20100197651-A1 | Pyridazinone compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | US | disclosed |
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009158011-A1 | ALKYNYL ALCOHOLS AS KINASE INHIBITORS | AMGEN INC. (US) | 2009-12-30 | — | — | WO | disclosed |