Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502342 | 0.94 | ITGB3 (0.36) | ITGB3ITGAV | |
| SCHEMBL5202520 | 0.80 | ITGB3 (0.37) | ITGB3ITGAV | |
| SCHEMBL5204549 | 0.79 | ITGB3 (0.37) | ITGB3ITGAV | |
| SCHEMBL5207840 | 0.78 | MAPT (0.32) | ITGB3ITGAV | |
| SCHEMBL14431254 | 0.78 | MAPT (0.32) | ITGB3ITGAV | |
| SCHEMBL6493594 | 0.73 | ITGB3 (0.43) | ITGB3ITGAV | |
| SCHEMBL6493907 | 0.72 | ITGB3 (0.42) | ITGB3ITGAV | |
| SCHEMBL6503598 | 0.71 | ITGB1 (0.37) | ITGB3ITGAV | |
| SCHEMBL5203778 | 0.67 | ITGB3 (0.32) | ITGB3ITGAV | |
| SCHEMBL6494232 | 0.65 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124824-B1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1124824-A1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026212-A1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2000-05-11 | — | — | WO | disclosed |