Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493907 | 0.94 | ITGB3 (0.42) | ITGB3ITGAVTYRITGA2BPPARA | |
| SCHEMBL5202520 | 0.90 | ITGB3 (0.37) | ITGB3ITGAVTACR1CTSKALDH1A1 | |
| SCHEMBL6493594 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVTYRITGA2BALDH1A1 | |
| SCHEMBL5210309 | 0.74 | TYR (0.41) | ITGB3ITGAVTYRITGA2BPPARA | |
| SCHEMBL6502342 | 0.73 | ITGB3 (0.36) | ITGB3ITGAVITGA2BPPARATSHR | |
| SCHEMBL27406870 | 0.68 | CTSL (0.48) | ITGB3ITGAVTYRTSHRTACR1 | |
| SCHEMBL7361913 | 0.68 | ALOX15 (0.40) | ITGB3ITGAVITGA2BCTSK | |
| SCHEMBL6440663 | 0.65 | CTSL (0.64) | TYRTACR1CTSKALDH1A1 | |
| SCHEMBL6440666 | 0.65 | CTSL (0.64) | TYRTACR1CTSKALDH1A1 | |
| SCHEMBL4679583 | 0.64 | USP2 (0.39) | ITGB3ITGAVTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124824-B1 | CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2007-08-22 | — | — | EP | disclosed |