Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204611 | 1.00 | NPC1 (0.50) | NPC1RAB9AKDM4EMAPK1CYP19A1 | |
| SCHEMBL18327182 | 1.00 | NPC1 (0.50) | NPC1RAB9AKDM4EMAPK1CYP19A1 | |
| SCHEMBL5205616 | 0.84 | ELANE (0.45) | RAB9AKDM4EMAPK1PARP1LMNA | |
| SCHEMBL5206138 | 0.84 | LMNA (0.52) | NPC1RAB9ATSHRPARP1LMNA | |
| SCHEMBL5205858 | 0.84 | ELANE (0.45) | RAB9AKDM4EMAPK1PARP1LMNA | |
| SCHEMBL5206016 | 0.84 | LMNA (0.52) | NPC1RAB9ATSHRPARP1LMNA | |
| SCHEMBL5201790 | 0.83 | RXFP1 (0.47) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL5205877 | 0.83 | RXFP1 (0.47) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL5203413 | 0.82 | NPC1 (0.53) | NPC1RAB9AKDM4EMAPK1TSHR | |
| SCHEMBL5203419 | 0.82 | NPC1 (0.53) | NPC1RAB9AKDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230105618-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-04-06 | — | — | US | disclosed |
| US-20200350503-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2020-11-05 | — | — | US | disclosed |
| US-20160372688-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-12-22 | — | — | US | disclosed |
| EP-1458706-B1 | DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR | CJ CORP (KR) | 2007-07-11 | — | — | EP | disclosed |
| US-7169929-B2 | Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | CJ CORP. (KR) | 2007-01-30 | — | — | US | disclosed |
| US-7135572-B2 | Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | CJ CORP (KR) | 2006-11-14 | — | — | US | disclosed |
| US-20060009495-A1 | Diary 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | CJ CORP. (KR) | 2006-01-12 | — | — | US | disclosed |
| EP-1458706-A4 | DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR | CJ CORP (KR) | 2005-06-08 | — | — | EP | disclosed |
| US-20050075373-A1 | Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | CJ CORP. (KR) | 2005-04-07 | — | — | US | disclosed |
| EP-1458706-A1 | DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR | CJ Corp. (KR) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003055875-A1 | DIARYL 1,2,4-TRIAZOLE DERIVATIVES AS A HIGHLY SELECTIVE CYCLOOXYGENASE-2 INHIBITOR | CJ CORP. (KR) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009495-A1 | Diary 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | PTGS1, PTGS2, PTGES2 | NPC1 4852/4885RAB9A 4647/4885KDM4E 1122/4885 |
| US-20160372688-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | PPOX, EHD1, INTS9 | NPC1 3520/4885RAB9A 3280/4885KDM4E 2698/4885 |
| US-20200350503-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | PPOX, EHD1, INTS9 | NPC1 3520/4885RAB9A 3280/4885KDM4E 2698/4885 |
| US-20050075373-A1 | Diaryl 1,2,4-triazole derivatives as a highly selective cyclooxygenase-2 inhibitor | PTGS1, PTGS2, PTGES2 | NPC1 4850/4885RAB9A 4686/4885KDM4E 1572/4885 |
| US-20230105618-A1 | IRIDIUM COMPLEX, LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | PPOX, EHD1, INTS9 | NPC1 3520/4885RAB9A 3280/4885KDM4E 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.