Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206008 | 0.68 | HRH2 (0.41) | MEN1KMT2AHRH2HTR2AHTR2C | |
| SCHEMBL4857534 | 0.68 | DRD4 (0.40) | ALDH1A1TSHRMEN1KMT2AHRH2 | |
| SCHEMBL5202270 | 0.65 | MAPT (0.43) | ALDH1A1MEN1KMT2ADRD4RXFP1 | |
| SCHEMBL26463371 | 0.62 | ALDH1A1 (0.52) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8685429 | 0.62 | MEN1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1923480 | 0.61 | USP10 (0.44) | RXFP1 | |
| SCHEMBL2161626 | 0.59 | GAA (0.52) | TSHRMEN1KMT2ADRD4 | |
| SCHEMBL4004199 | 0.59 | HSD11B1 (0.57) | ALDH1A1MEN1KMT2AHTR2ADRD4 | |
| SCHEMBL5201910 | 0.59 | NPC1 (0.42) | MEN1KMT2AHRH2RXFP1 | |
| SCHEMBL6827705 | 0.59 | DRD2 (0.52) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654253-B1 | SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-01-03 | — | — | EP | claimed |