Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5204591 | 0.91 | F10 (0.33) | F10FLT3F2PARP1 | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.90 | IKBKB (0.33) | F10FLT3F2PARP1RORC | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.88 | FLT3 (0.39) | FLT3RORCNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.88 | FLT3 (0.37) | FLT3RORCNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5206308 | 0.87 | MEN1 (0.31) | F10FLT3PARP1FABP4FABP5 | |
| Trifluoroacetic Acid SCHEMBL5208332 | 0.86 | FLT3 (0.35) | FLT3F2RORCNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5209056 | 0.85 | F2 (0.34) | F10FLT3F2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL5204002 | 0.84 | FLT3 (0.38) | FLT3RORCNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.84 | ALDH1A1 (0.40) | FLT3RORCNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5207943 | 0.84 | KIF11 (0.44) | FLT3PARP1RORCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |