Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5204258 | 0.91 | F10 (0.34) | F10FLT3PARP1F2 | |
| Trifluoroacetic Acid SCHEMBL5208518 | 0.89 | FLT3 (0.38) | FLT3MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL5204634 | 0.87 | MAPK10 (0.36) | PIK3CAPIK3CBMAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.86 | IKBKB (0.33) | F10FLT3PARP1F2 | |
| Trifluoroacetic Acid SCHEMBL5209006 | 0.86 | PIK3CA (0.33) | FLT3PIK3CAPIK3CBPARP1GPBAR1 | |
| Trifluoroacetic Acid SCHEMBL5205966 | 0.84 | PDE4D (0.39) | MAPT | |
| Trifluoroacetic Acid SCHEMBL5206308 | 0.84 | MEN1 (0.31) | F10FLT3PARP1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5203620 | 0.82 | PIK3CA (0.33) | PIK3CAPIK3CBGPBAR1MAPTKMT2A | |
| SCHEMBL5209500 | 0.80 | ENPP2 (0.36) | FLT3PARP1MAPTF2 | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.79 | FLT3 (0.39) | FLT3MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |