Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5206929 | 0.90 | NPSR1 (0.34) | MEN1ALDH1A1RECQLKMT2ANPSR1 | |
| SCHEMBL5209500 | 0.90 | ENPP2 (0.36) | ALDH1A1GRM1KLKB1KLK1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.88 | IKBKB (0.33) | NPSR1F10KLKB1KLK1FLT3 | |
| Trifluoroacetic Acid SCHEMBL4812316 | 0.88 | ALDH1A1 (0.33) | MEN1ALDH1A1RECQLKMT2ANPSR1 | |
| Trifluoroacetic Acid SCHEMBL5204258 | 0.87 | F10 (0.34) | F10FLT3FABP4FABP5PARP1 | |
| Trifluoroacetic Acid SCHEMBL4809946 | 0.87 | PDE4D (0.36) | ALDH1A1NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5208994 | 0.85 | ENPP2 (0.36) | MEN1ALDH1A1KMT2ANPSR1KLKB1 | |
| Trifluoroacetic Acid SCHEMBL5204591 | 0.84 | F10 (0.33) | KMT2AF10FLT3PARP1 | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.83 | ENPP2 (0.34) | KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.83 | PDE4D (0.37) | MEN1ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |