Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411850 | 0.83 | CA1 (0.36) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL24398644 | 0.81 | ALDH1A1 (0.59) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL31134158 | 0.81 | ALDH1A1 (0.59) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL3714765 | 0.80 | LMNA (0.35) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL7189375 | 0.80 | CYP1A2 (0.40) | CA1CA2CA9MAPT | |
| SCHEMBL7189386 | 0.80 | CYP1A2 (0.40) | CA1CA2CA9MAPT | |
| SCHEMBL4868031 | 0.79 | CA1 (0.41) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL12098518 | 0.79 | RXRA (0.46) | ALDH1A1MAPTMAPK1SMN1; SMN2HPGD | |
| SCHEMBL7366742 | 0.77 | SCN10A (0.33) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL4261454 | 0.76 | CA1 (0.31) | CA1CA2CA9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111822053-B | Chiral polysulfonate diamine-metal catalyst and synthesis and application thereof | 中山大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-111822053-A | Chiral polysulfonate diamine-metal catalyst and synthesis and application thereof | 中山大学 | 2020-10-27 | — | — | CN | disclosed |
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| CN-1834091-A | Sustituted Gly derivative for treating diabetes and adiposis | SHENG ZELIN (CN) | 2006-09-20 | — | — | CN | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003024909-A1 | METHOD OF PREPARING SYMMETRICAL POLYHYDROXYSTILBENES | L'OREAL (FR) | 2003-03-27 | — | — | WO | disclosed |
| CN-1083833-C | Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents | SCHERING CORP (US) | 2002-05-01 | — | — | CN | disclosed |
| EP-0792264-B1 | SULFUR-SUBSTITUTED AZETIDINONE COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | SCHERING CORP (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-0805132-B1 | Method of producing styrene derivatives | HONSHU CHEMICAL IND (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5763560-A | TREATING BENZALDEHYDE DERIVATIVE WITH ZINC AND ACTIVE CHLORIDE IN AN ORGANIC SOLVENT | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| CN-1174548-A | Sulfur-substituted azetidinone compounds useful as cholesterol lowering agents | SCHERING CORP (US) | 1998-02-25 | — | — | CN | disclosed |
| US-5686478-A | Endothelin antagonists | MERCK & CO. INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0805132-A1 | Method of producing styrene derivatives | HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5633246-A | Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents | SCHERING CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5624920-A | Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents | SCHERING CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |