Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789832 | 0.78 | GABRA1 (0.41) | ALDH1A1 | |
| SCHEMBL4432928 | 0.77 | CTRC (0.40) | TLR8 | |
| SCHEMBL30462202 | 0.74 | TAAR1 (0.50) | TLR8ALDH1A1 | |
| SCHEMBL8076090 | 0.74 | TAAR1 (0.50) | TLR8ALDH1A1 | |
| SCHEMBL10661020 | 0.74 | LIPG (0.47) | TDP1 | |
| SCHEMBL6558282 | 0.74 | LIPG (0.47) | TDP1 | |
| SCHEMBL9322497 | 0.72 | PPARG (0.32) | — | |
| SCHEMBL11519509 | 0.71 | USP2 (0.34) | TLR8USP2ALDH1A1HPGDTDP1 | |
| SCHEMBL9689790 | 0.71 | — | — | |
| SCHEMBL248775 | 0.69 | TAAR1 (0.48) | TLR8USP2ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |