SCHEMBL520500

SCHEMBL520500

Nc1ccc(F)cc1B(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KEAP1 Q14145 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 2/20 0.40
GAA P10253 1/20 0.40
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
HDAC1 Q13547 3/20 0.35
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
ACHE P22303 1/20 0.34
GRM5 P41594 1/20 0.33
PARP1 P09874 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955598 1.00 ALDH1A1 (0.50) ALDH1A1KEAP1L3MBTL1HTTGAA
Hydrochloric Acid SCHEMBL29951103 0.98 ALDH1A1 (0.48) ALDH1A1KEAP1L3MBTL1HTTGAA
SCHEMBL3781322 0.82 ALDH1A1 (0.44) ALDH1A1KEAP1L3MBTL1HTTGAA
SCHEMBL4963 0.76 CA3 (0.48) ALDH1A1HTTORAI1ORAI2ORAI3
SCHEMBL28730410 0.76 ALDH1A1 (0.43) ALDH1A1GAAKDM4E
SCHEMBL29406861 0.76 CA3 (0.48) ALDH1A1HTTORAI1ORAI2ORAI3
SCHEMBL3791253 0.74 CA14 (0.43) ALDH1A1HTTCA3CA6CA9
SCHEMBL319589 0.74 CA3 (0.46) ALDH1A1ORAI1ORAI2ORAI3TRPV6
SCHEMBL337813 0.74 ACHE (0.41) ALDH1A1HTTORAI1ORAI2ORAI3
SCHEMBL31555013 0.74 ACHE (0.41) ALDH1A1HTTORAI1ORAI2ORAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120056488-A Preparation method of copper-free and steel-free carbon fiber composite friction plate applied to electric bicycle 浙江万赛汽车零部件股份有限公司 2025-05-30 CN claimed
CN-119215681-A Method for constructing mixed matrix membrane with continuous channels by regulating microphase separation structure 大连理工大学 2024-12-31 CN claimed
CN-118324696-A Key raw material for detecting bixafen as well as preparation method and application thereof 福建省农业科学院农业质量标准与检测技术研究所 2024-07-12 CN claimed
CN-110678729-B Catalyst for reversing formaldehyde adducts and crosslinking 豪夫迈·罗氏有限公司 2023-04-11 CN claimed
US-10995104-B2 Catalysts for reversing formaldehyde adducts and crosslinks ROCHE MOLECULAR SYSTEM, INC. (US) 2021-05-04 US claimed
CN-110987820-B Glucose responsive photonic crystal sensor, preparation method and use method thereof 武汉理工大学 2020-10-30 CN claimed
CN-110987820-A Glucose responsive photonic crystal sensor, preparation method and use method thereof 武汉理工大学 2020-04-10 CN claimed
EP-3631408-A1 CATALYSTS FOR REVERSING FORMALDEHYDE ADDUCTS AND CROSSLINKS Roche Diagnostics GmbH (DE) 2020-04-08 EP claimed
CN-110678729-A Catalyst for reversing formaldehyde adducts and crosslinking 豪夫迈·罗氏有限公司 2020-01-10 CN claimed
US-20180370992-A1 Catalysts for reversing formaldehyde adducts and crosslinks ROCHE MOLECULAR SYSTEMS, INC. 2018-12-27 US claimed
WO-2018219997-A1 CATALYSTS FOR REVERSING FORMALDEHYDE ADDUCTS AND CROSSLINKS ROCHE DIAGNOSTICS GMBH (DE) 2018-12-06 WO claimed
CN-120056488-A Preparation method of copper-free and steel-free carbon fiber composite friction plate applied to electric bicycle 浙江万赛汽车零部件股份有限公司 2025-05-30 CN disclosed
CN-119215681-A Method for constructing mixed matrix membrane with continuous channels by regulating microphase separation structure 大连理工大学 2024-12-31 CN disclosed
CN-118324696-A Key raw material for detecting bixafen as well as preparation method and application thereof 福建省农业科学院农业质量标准与检测技术研究所 2024-07-12 CN disclosed
CN-116854999-B Quick-response photonic crystal heterogeneous gel material, preparation method and application thereof 武汉理工大学 2023-12-19 CN disclosed
WO-2011119565-A1 IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2011-09-29 WO disclosed
US-20110182812-A1 Imaging Agents for Detecting Neurological Disorders SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2011-07-28 US disclosed
WO-2010071885-A1 PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS CEPHALON, INC. (US) 2010-06-24 WO disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180370992-A1 Catalysts for reversing formaldehyde adducts and crosslinks FBL, PCNA, UNG ALDH1A1 724/4885KEAP1 1170/4885L3MBTL1 1198/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ALDH1A1 4339/4885KEAP1 1245/4885L3MBTL1 3838/4885
US-20110182812-A1 Imaging Agents for Detecting Neurological Disorders MAPT, APP, PSEN1 ALDH1A1 3926/4885KEAP1 965/4885L3MBTL1 3845/4885
US-10995104-B2 Catalysts for reversing formaldehyde adducts and crosslinks FBL, PCNA, UNG ALDH1A1 724/4885KEAP1 1170/4885L3MBTL1 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.