Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998943 | 0.95 | OPRM1 (0.33) | LOXL2ADRA2CKMT2AL3MBTL1CFD | |
| SCHEMBL5628892 | 0.90 | ADRA2C (0.35) | LOXL2ADRA2CF2F10KMT2A | |
| SCHEMBL5208096 | 0.81 | KMT2A (0.36) | KMT2A | |
| SCHEMBL5210877 | 0.77 | ADRA2C (0.52) | LOXL2ADRA2CF2KMT2AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5209569 | 0.75 | F2 (0.31) | F2 | |
| SCHEMBL5204891 | 0.72 | KMT2A (0.33) | ADRA2CF2F10KMT2A | |
| SCHEMBL5209352 | 0.72 | F2 (0.34) | ADRA2CF2F10KMT2A | |
| Trifluoroacetic Acid SCHEMBL5206988 | 0.71 | FOLH1 (0.35) | ADRA2CF2F10OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5629214 | 0.70 | F2 (0.32) | ADRA2CF2F10 | |
| SCHEMBL5208588 | 0.70 | F2 (0.34) | LOXL2ADRA2CF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |