Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628892 | 0.89 | ADRA2C (0.35) | KMT2AGAA | |
| SCHEMBL5205927 | 0.81 | LOXL2 (0.34) | KMT2A | |
| SCHEMBL6998943 | 0.80 | OPRM1 (0.33) | KMT2A | |
| Trifluoroacetic Acid SCHEMBL5209569 | 0.77 | F2 (0.31) | — | |
| SCHEMBL5204891 | 0.75 | KMT2A (0.33) | KMT2AALDH1A1MEN1POLB | |
| SCHEMBL5209352 | 0.72 | F2 (0.34) | KMT2AMEN1POLB | |
| SCHEMBL5210877 | 0.70 | ADRA2C (0.52) | KMT2AGAAMEN1 | |
| Trifluoroacetic Acid SCHEMBL5209705 | 0.69 | F2 (0.33) | — | |
| SCHEMBL5209456 | 0.69 | CNR2 (0.42) | KMT2AALDH1A1GAAHSD17B10MEN1 | |
| Trifluoroacetic Acid SCHEMBL5206988 | 0.68 | FOLH1 (0.35) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |