Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105705 | 0.84 | TSHR (0.69) | HPGDKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL16140981 | 0.84 | KMT2A (1.00) | HPGDKMT2AMEN1TDP1NPC1 | |
| SCHEMBL13841452 | 0.83 | POLB (0.74) | HPGDKMT2AMEN1TDP1HTT | |
| SCHEMBL10016247 | 0.83 | MEN1 (0.55) | HPGDKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL971460 | 0.81 | HPGD (1.00) | HPGDKMT2AMEN1TDP1NPC1 | |
| SCHEMBL5347276 | 0.81 | RAB9A (0.53) | HPGDKMT2AMEN1TDP1NPC1 | |
| SCHEMBL6663354 | 0.81 | MEN1 (0.53) | HPGDKMT2AMEN1RAB9AHTT | |
| SCHEMBL680052 | 0.81 | ALDH1A1 (0.69) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL307601 | 0.81 | MAPT (0.59) | HPGDKMT2AMEN1RAB9AHTT | |
| SCHEMBL1225424 | 0.81 | KMT2A (0.77) | HPGDKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554246-B1 | DIHYDROPYRIDINONE DERIVATIVES AS HNE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| US-20060100207-A1 | Dihydropyridinone derivatives | BAYER HEALTHCARE AG (DE) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100207-A1 | Dihydropyridinone derivatives | TNNI3, DHPS, TNNT2 | HPGD 6/4885KMT2A 2664/4885MEN1 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.