Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CCR2 | P41597 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126947 | 0.95 | POLB (0.75) | POLBMAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL3151686 | 0.89 | POLB (0.71) | POLBCCR2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8125916 | 0.86 | MEN1 (0.68) | POLBMAPTALDH1A1L3MBTL1MCHR1 | |
| SCHEMBL5626457 | 0.84 | ALDH1A1 (0.74) | CCR2MAPTALDH1A1L3MBTL1NPBWR1 | |
| SCHEMBL7985192 | 0.83 | ALDH1A1 (0.62) | POLBCCR2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL25368316 | 0.82 | POLB (0.73) | POLBMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15347670 | 0.82 | POLB (0.73) | POLBMAPTALDH1A1NPBWR1MCHR1 | |
| SCHEMBL4506302 | 0.82 | POLB (0.65) | POLBMAPTALDH1A1NPBWR1MCHR1 | |
| SCHEMBL3156886 | 0.81 | KDM4E (0.73) | POLBCCR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7048817 | 0.81 | MAPT (0.85) | POLBMAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | disclosed |
| EP-1417184-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014093-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | KRT18, HPD, PPOX | POLB 504/4885CCR2 2466/4885MAPT 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.