Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.33 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207099 | 1.00 | EGFR (0.36) | EGFRCYSLTR2CYSLTR1PPARAPOLM | |
| SCHEMBL5206380 | 0.86 | LTA4H (0.37) | — | |
| SCHEMBL5206374 | 0.86 | LTA4H (0.37) | — | |
| SCHEMBL5207094 | 0.80 | PPARA (0.35) | CYSLTR2CYSLTR1PPARAPOLMPOLK | |
| SCHEMBL5206912 | 0.78 | F7 (0.43) | KDM4ETNNC1 | |
| SCHEMBL5207595 | 0.78 | L3MBTL1 (0.34) | CYSLTR2CYSLTR1KDM4EL3MBTL1TNNC1 | |
| SCHEMBL5207607 | 0.78 | L3MBTL1 (0.34) | CYSLTR2CYSLTR1KDM4EL3MBTL1TNNC1 | |
| SCHEMBL5206898 | 0.78 | F7 (0.43) | KDM4ETNNC1 | |
| SCHEMBL6050423 | 0.73 | MEN1 (0.40) | MEN1KMT2APPARG | |
| SCHEMBL16957876 | 0.72 | ALDH1A1 (0.40) | KDM4EMEN1KMT2AGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |