SCHEMBL5208692

SCHEMBL5208692

O=C(O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.71
PTGS1 P23219 6/20 0.56
PTGS2 P35354 6/20 0.56
FAAH O00519 3/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
PKM P14618 2/20 0.41
HSP90AA1 P07900 1/20 0.41
TLR9 Q9NR96 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GPR35 Q9HC97 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10079339 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL13733359 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL22311909 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL16933147 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL27420754 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL15215618 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL17732171 1.00 MGLL (0.71) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL5828798 0.98 MGLL (0.68) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL18157046 0.90 PTGS1 (0.62) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL10126653 0.90 MGLL (0.67) MGLLPTGS1PTGS2FAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 EP disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 US disclosed
WO-2025134068-A1 ANTIBODY DRUG CONJUGATES TARGETING PROTEINOPATHIES, AND USES THEREOF AC IMMUNE SA (CH) 2025-06-26 WO disclosed
US-20250152722-A1 DRUG CONJUGATE OF GLUCOCORTICOID SHANGHAI SENHUI MEDICINE CO., LTD. (CN) 2025-05-15 US disclosed
WO-2025064709-A1 SURFACE-MODIFIED FIBERS AND ARTICLES AND METHODS OF MAKING THE SAME ORIGIN MATERIALS OPERATING, INC. (US) 2025-03-27 WO disclosed
EP-4470569-A1 DRUG CONJUGATE OF GLUCOCORTICOID Shanghai Shengdi Pharmaceutical Co., Ltd (CN) 2024-12-04 EP disclosed
US-20240293570-A1 HIGHLY STABLE TARGETED LINKER-DRUG CONJUGATE CHENGDU SCIMOUNT PHARMATECH CO., LTD. (CN) 2024-09-05 US disclosed
EP-4420682-A1 HIGHLY-STABLE TARGETED LINKER-DRUG CONJUGATE Chengdu Scimount Pharmatech Co., Ltd. (CN) 2024-08-28 EP disclosed
CN-118236514-A Antibody-glucocorticoid conjugates and uses thereof 津药生物科技(天津)有限公司 2024-06-25 CN disclosed
WO-2016203432-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2016-12-22 WO disclosed
US-20160311853-A1 CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2016-10-27 US disclosed
EP-3082877-A2 CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF Novartis AG (CH) 2016-10-26 EP disclosed
WO-2016146638-A1 CRYPTOPHYCIN-BASED ANTIBODY-DRUG CONJUGATES WITH NOVEL SELF-IMMOLATIVE LINKERS EXIRIS S.R.L. (IT) 2016-09-22 WO disclosed
EP-3069734-A1 CRYPTOPHYCIN-BASED ANTIBODY-DRUG CONJUGATES WITH NOVEL SELF-IMMOLATIVE LINKERS Exiris S.r.l. (IT) 2016-09-21 EP disclosed
WO-2016071856-A1 AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASE NOVARTIS AG (CH) 2016-05-12 WO disclosed
WO-2015095301-A2 CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF IRM LLC (BM) 2015-06-25 WO disclosed
EP-1603930-B1 PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS KTB TUMORFORSCHUNGS GMBH (DE) 2007-08-29 EP disclosed
US-7141691-B2 Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands KTB TUMORFORSCHUNGS GMBH (DE) 2006-11-28 US disclosed
US-20060089341-A1 Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands KTB TUMORFORSCHUNGS GMBH (DE) 2006-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060089341-A1 Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands DDB1, DCLRE1A, PDCD1LG2 MGLL 4755/4885PTGS1 2109/4885PTGS2 3364/4885
US-20160311853-A1 CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF CD47, NGLY1, VIP MGLL 4602/4885PTGS1 4232/4885PTGS2 4661/4885
US-20250152722-A1 DRUG CONJUGATE OF GLUCOCORTICOID SHBG, CYP17A1, HSD17B7 MGLL 2673/4885PTGS1 979/4885PTGS2 2340/4885
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 MGLL 2400/4885PTGS1 740/4885PTGS2 1315/4885
US-20240293570-A1 HIGHLY STABLE TARGETED LINKER-DRUG CONJUGATE DARS1, FCGR2A, CD44 MGLL 4872/4885PTGS1 4460/4885PTGS2 4501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.