Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5206929 | 0.93 | NPSR1 (0.34) | FLT3NPC1RAB9ARXFP1RORC | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.92 | PDE4D (0.37) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL5204674 | 0.91 | ENPP2 (0.34) | ENPP2NPC1RAB9AMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.90 | ENPP2 (0.34) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL4809946 | 0.87 | PDE4D (0.36) | MAPTALDH1A1KDM4EHSD17B10GAA | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.86 | FLT3 (0.39) | FLT3NPC1RAB9ARXFP1RORC | |
| SCHEMBL5209500 | 0.86 | ENPP2 (0.36) | ENPP2FLT3MAPTALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL5206023 | 0.86 | ENPP2 (0.36) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5211197 | 0.86 | FLT3 (0.36) | FLT3NPC1RAB9ARXFP1RORC | |
| Trifluoroacetic Acid SCHEMBL5206308 | 0.85 | MEN1 (0.31) | FLT3MEN1KMT2AALDH1A1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |