Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5208994 | 0.86 | ENPP2 (0.36) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5208291 | 0.85 | MAPT (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL5203620 | 0.84 | PIK3CA (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL5204674 | 0.84 | ENPP2 (0.34) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL4809992 | 0.83 | ENPP2 (0.41) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.83 | ENPP2 (0.34) | ENPP2KLKB1KLK1 | |
| SCHEMBL5210132 | 0.82 | F2 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.82 | PDE4D (0.37) | — | |
| SCHEMBL6991435 | 0.79 | F2 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL5206929 | 0.79 | NPSR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |