Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | KLK1 | P06870 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5206308 | 0.90 | MEN1 (0.31) | FLT3KLKB1KLK1PARP1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5208994 | 0.86 | ENPP2 (0.36) | ENPP2FLT3KLKB1KLK1ABCB1 | |
| Trifluoroacetic Acid SCHEMBL5204674 | 0.84 | ENPP2 (0.34) | ENPP2KLKB1KLK1ALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.83 | ENPP2 (0.34) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.83 | IKBKB (0.33) | FLT3KLKB1KLK1PARP1IKBKB | |
| Trifluoroacetic Acid SCHEMBL5204258 | 0.83 | F10 (0.34) | FLT3PARP1F2 | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.82 | PDE4D (0.37) | ADORA2AADORA1ALDH1A1TDP1KDM4E | |
| Trifluoroacetic Acid SCHEMBL5204591 | 0.80 | F10 (0.33) | FLT3PARP1F2MAPT | |
| Trifluoroacetic Acid SCHEMBL5206929 | 0.79 | NPSR1 (0.34) | FLT3PARP1ALDH1A1GRM1POLB | |
| Trifluoroacetic Acid SCHEMBL5206023 | 0.79 | ENPP2 (0.36) | ENPP2KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |