Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5208994 | 0.90 | ENPP2 (0.36) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5204674 | 0.88 | ENPP2 (0.34) | ENPP2KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.88 | MEN1 (0.31) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5209056 | 0.87 | F2 (0.34) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5211226 | 0.87 | PDE4D (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL5206929 | 0.85 | NPSR1 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL5209006 | 0.84 | PIK3CA (0.33) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5206308 | 0.83 | MEN1 (0.31) | KLKB1KLK1 | |
| Trifluoroacetic Acid SCHEMBL5206023 | 0.83 | ENPP2 (0.36) | ENPP2KLKB1KLK1 | |
| SCHEMBL5209500 | 0.83 | ENPP2 (0.36) | ENPP2KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |