Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5209056 | 0.91 | F2 (0.34) | OPRM1OPRD1MEN1POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5208518 | 0.89 | FLT3 (0.38) | MEN1KMT2ANPSR1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5204634 | 0.87 | MAPK10 (0.36) | PIK3CAPIK3CBMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5204591 | 0.86 | F10 (0.33) | PIK3CAPIK3CBGPBAR1KMT2AFLT3 | |
| Trifluoroacetic Acid SCHEMBL5205966 | 0.86 | PDE4D (0.39) | NPSR1 | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.85 | MEN1 (0.31) | OPRM1OPRD1MEN1POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5209115 | 0.84 | ENPP2 (0.34) | OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL5203620 | 0.81 | PIK3CA (0.33) | PIK3CAPIK3CBGPBAR1MEN1POLB | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.79 | FLT3 (0.39) | MEN1POLBKMT2ANPSR1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.79 | FLT3 (0.37) | MEN1POLBKMT2AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |