Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212436 | 0.91 | HRH3 (0.59) | HRH3L3MBTL3L3MBTL1KCNH2MBTD1 | |
| SCHEMBL5208300 | 0.85 | L3MBTL3 (0.62) | HRH3SMN1; SMN2L3MBTL3L3MBTL1MBTD1 | |
| Hydrochloric Acid SCHEMBL5213432 | 0.84 | L3MBTL3 (0.60) | HRH3SMN1; SMN2L3MBTL3L3MBTL1KCNH2 | |
| SCHEMBL5212817 | 0.84 | HRH3 (0.61) | HRH3 | |
| SCHEMBL5208889 | 0.84 | HRH3 (0.56) | HRH3SMN1; SMN2AKR1C3 | |
| SCHEMBL14431499 | 0.83 | HRH3 (0.75) | HRH3 | |
| SCHEMBL5210105 | 0.83 | HRH3 (0.60) | HRH3HRH1 | |
| SCHEMBL5212438 | 0.80 | HRH3 (0.60) | HRH3KCNH2HRH1 | |
| SCHEMBL5211397 | 0.80 | HRH3 (0.57) | HRH3HRH1 | |
| SCHEMBL5209593 | 0.80 | ALDH1A1 (0.64) | HRH3SMN1; SMN2L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |