Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 4/20 | 0.32 |
| ▸ | PSMA8 | Q8TAA3 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619541 | 1.00 | RAB9A (0.33) | RAB9ANPC1PSMB5PSMB1PSMB2 | |
| SCHEMBL5212107 | 0.94 | KDM4E (0.37) | RAB9ALMNATSHRGAACYP1A2 | |
| SCHEMBL5215434 | 0.92 | GPR88 (0.33) | RAB9ANPC1PSMB5TSHRSCD5 | |
| SCHEMBL5215066 | 0.89 | GPR88 (0.33) | GAAGPR88CYP3A4ALDH1A1MAPT | |
| SCHEMBL14443145 | 0.88 | GPR119 (0.32) | RAB9ANPC1LMNATSHR | |
| SCHEMBL5215885 | 0.85 | ADORA2B (0.33) | LMNATSHRGPR88ALDH1A1 | |
| SCHEMBL5213331 | 0.85 | LMNA (0.32) | LMNAGPR88CYP2D6 | |
| SCHEMBL5214156 | 0.84 | MAPT (0.36) | RAB9ANPC1LMNAGAATHRB | |
| SCHEMBL5641473 | 0.83 | SMN1; SMN2 (0.36) | RAB9ANPC1TP53CCR5HTT | |
| SCHEMBL6631345 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259163-B2 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as HCV inhibitors | GLAXO GROUP LIMITED (GB) | 2007-08-21 | — | — | US | disclosed |
| EP-1440069-B1 | 4-(6-MEMBERED)-HETEROARYL ACYL PYRROLIDINE DERIVATIVES AS HCV INHIBITORS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
| US-20050043390-A1 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as hcv inhibitors | GLAXO GROUP LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043390-A1 | 4-(6-membered)-heteroaryl acyl pyrrolidine derivatives as hcv inhibitors | NR1H3, NR1H2, NR1I3 | RAB9A 1893/4885NPC1 197/4885PSMB5 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.