Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215839 | 0.85 | VDR (0.38) | VDRIDO1TSHRAGTR1AGTR2 | |
| SCHEMBL5672551 | 0.85 | VDR (0.39) | VDRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5215694 | 0.83 | TBXA2R (0.35) | VDRIDO1CYP1A2CYP2C19MEN1 | |
| SCHEMBL5673979 | 0.82 | VDR (0.38) | VDRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5220085 | 0.81 | VDR (0.42) | VDRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5672549 | 0.81 | TRAP1 (0.40) | VDRPPARGALDH1A1KDM4EHSP90B1 | |
| SCHEMBL5675509 | 0.81 | ALDH1A1 (0.42) | VDRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5673814 | 0.81 | MEN1 (0.43) | NPSR1MEN1KMT2ADCTPP1SMN1; SMN2 | |
| SCHEMBL5675513 | 0.81 | ALDH1A1 (0.42) | VDRNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5674041 | 0.79 | ALDH1A1 (0.37) | VDRNPSR1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |