Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216238 | 0.88 | KDM4E (0.33) | LMNATSHRHTR4 | |
| SCHEMBL5219348 | 0.86 | KDM4E (0.39) | LMNATSHR | |
| SCHEMBL5213847 | 0.83 | ALDH1A1 (0.31) | ALDH1A1HTR4 | |
| SCHEMBL5212276 | 0.83 | IKBKB (0.32) | IKBKBHTR4L3MBTL1 | |
| SCHEMBL5215599 | 0.81 | KDM4E (0.34) | ALDH1A1CYP1A2HTR4 | |
| SCHEMBL5213651 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HTR4 | |
| SCHEMBL5215519 | 0.80 | HTR4 (0.33) | LMNAHTR4 | |
| SCHEMBL5216323 | 0.80 | NPC1 (0.32) | — | |
| SCHEMBL5216607 | 0.79 | GNAO1 (0.36) | LMNAALDH1A1SMN1; SMN2CYP1A2HTR4 | |
| SCHEMBL5218969 | 0.79 | HTR4 (0.35) | LMNAALDH1A1SMN1; SMN2CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112270-B1 | DIHYDROBENZODIOXINE CARBOXAMIDE AND KETONE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |