Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894694 | 0.79 | LMNA (0.53) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL4884706 | 0.74 | LMNA (0.47) | VCAM1POLBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL5216082 | 0.74 | BDKRB1 (0.43) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL4886776 | 0.73 | LMNA (0.67) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL4886782 | 0.73 | LMNA (0.58) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5388753 | 0.73 | BDKRB1 (0.48) | VCAM1POLBMEN1KMT2A | |
| SCHEMBL5384492 | 0.70 | BDKRB1 (0.48) | POLBMEN1KMT2A | |
| SCHEMBL6516177 | 0.69 | SIRT6 (0.50) | SMN1; SMN2LMNAMEN1KMT2AAR | |
| SCHEMBL29811879 | 0.69 | SIRT6 (0.50) | SMN1; SMN2LMNAMEN1KMT2AAR | |
| Hydrochloric Acid SCHEMBL3277921 | 0.67 | SIRT6 (0.49) | SMN1; SMN2LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812405-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048209-A1 | NOVEL BRADYKININ B1 ANTAGONISTS, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |