SCHEMBL5216256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL789722	0.82	MAPT (0.73)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL5215470	0.82	RAB9A (0.50)	RAB9ASMN1; SMN2NPC1MAPTLMNA
	SCHEMBL525057	0.80	RAB9A (0.60)	RAB9ASMN1; SMN2NPC1MAPTCYP1A2
	SCHEMBL5213498	0.79	CYP1A2 (0.57)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL31507493	0.79	RAB9A (0.54)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL5218406	0.78	SMN1; SMN2 (0.60)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL5041112	0.77	EGFR (0.73)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL4789312	0.77	SMN1; SMN2 (0.69)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL525373	0.77	MAOA (0.64)	EGFRRAB9ASMN1; SMN2NPC1MAPT
	SCHEMBL191185	0.77	ALDH1A1 (0.53)	EGFRRAB9ASMN1; SMN2NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.